Saturday Night Genealogy Fun -- What is Your Matrilineal Line?

From Randy over at Genea-Musings:

Dear genealogists everywhere, it's Saturday Night!  Time for some Genealogy FUN.

Your mission this week, should you decide to accept it, is to: 

 1) List your matrilineal line - your mother, her mother, etc. back to the first identifiable mother. Note: this line is how your mitochondrial DNA was passed to you!

2) Tell us if you have had your mitochondrial DNA tested, and if so, which Haplogroup you are in.

3) Post your responses on your own blog post, in Comments to this blog post, or in a Status line on Facebook or in your Stream at Google Plus.

4)  If you have done this before, please do your father's matrilineal line, or your grandfather's matrilineal line, or your spouse's matrilineal line.5)  Does this list spur you to find distant cousins that might share one of your matrilineal lines?  

Here's mine:

(1)  My matrilineal line:

- Mary Elizabeth Tapley (that's me!)

- Linda Irene Tapley, mother (b. Los Angeles, California)

- Ethel Irene Ranney Tapley, grandmother (b. July 6 1913 in Elsie, Clinton County, Michigan; d. Nov 12 1973 in Dublin, Laurens County, Georgia)

-  Bessie Alice Carter Ranney, great-grandmother (b. Feb 9 1883 in Milwaukee, Wisconsin; d. April 14 1960 in Redlands, San Bernardino County, California)  (She was adopted at birth.  I know nothing of her birth  family.)

- Sarah Melissa Schoonover, great-great-grandmother (b. July 13 1840; d. May 23 1918 in Elsie, Clinton County, Michigan)

- Sarah Ozmun, 3rd great-grandmother (b. Oct 23 1800; d. Nov 7 1870)

-  Sarah Jordan, 4th great-grandmother (b. Sept 29 1762 in New York; d. Aug 12 1812 in New York)

(2)  I have had my mitochondrial DNA tested and the Haplogroup I am in is U5a1a1.  This Haplogroup was centered in the Scandinavian countries.  

(3)  Done!  ;)

(4)  Will do in another post!

(5)  I am always eager to find near and distant cousins, especially on my mother's side because I know very few on that side of the family. 

Saturday Night Genealogy Fun - List Your Matrilineal Line(s)

From Randy Seaver over at Genea-Musings:

Hey genealogy buffs - it's Saturday Night again -- time for more Genealogy Fun!!
Your mission, should you decide to accept it, is to:

1) List your matrilineal line - your mother, her mother, etc. back to the first identifiable mother. Note: this line is how your mitochondrial DNA was passed to you!

2) Tell us if you have had your mitochondrial DNA tested, and if so, which Haplogroup you are in.

3) Post your responses on your own blog post, in Comments to this blog post, or in a Status line on Facebook or in your Stream at Google Plus.

4) If you have done this before, please do your father's matrilineal line, or your grandfather's matrilineal line, or your spouse's matriliuneal line.

5) Does this list spur you to find distant cousins that might share one of your matrilineal lines?


(1)

- Elizabeth "Liz" Tapley (me)

- Linda Irene Tapley (my mother)

- Ethel Irene Ranney (b. 1913 in Elsie, Michigan; d. 1973 in Dublin, Georgia), married Charles Tapley (grandmother)

- Bessie Alice Carter (b. 1883 in Milwaukee, Wisconsin; d. 1960 in Redlands, California), married Luther Boardman Ranney (great-grandmother)

- Sarah Melissa Schoonover (b. 1840; d. 1918 in Elsie, Michigan), married Charles K. Carter (great-great-grandmother)

- Sarah Ozman/Ozmun (b. 1800; d. 1870), married Richard Schoonover (3rd great-grandmother)

- Sarah Jordan (b. 1762 in New York; d. 1812 in New York), married Abraham Ozman/Ozmun (4th great-grandmother)

(2) Yes, I have had my mitochondrial DNA tested. I am in the maternal haplogroup U5a1a1.

(3) Done!

(4) N/A

(5) I was already interested in finding distant cousins from my matrilineal lines. I know so little about the Carters, Schoonovers, or Ozmans/Ozmuns. I have been contacted at 23andme.com by persons who are possible 3rd to 5th cousins or further out, but shame on me, I have not had a chance to follow up with any of them yet.

What my genotype indicates about my future

A few days ago, I shared the ancestry part of my DNA results.  Now I'd like to share the very interesting health results I received.

(1)  Disease Risk
         For someone with my genotype compared with average:
     
         I am at a higher risk for:

• Venous Thromboembolism (blood clots)
• Type 2 Diabetes
• Age-related Macular Degenration
• Atrial Fibrillation (irregular heart rhythm)
•  Psoriasis
• Colorectal Cancer
• Exfoliation Glaucoma (I already have glaucoma.) 
• Ulcerative Colitis
• Scleroderma (Limited Cutaneous Type)

        I am at a lower risk for:

•  Breast cancer
• Alzheimer's Disease
• Restless Leg Syndrome
• Rheumatoid Arthritis
• Melanoma
• Parkinson's Disease
• Multiple Sclerosis
• Celiac Disease
• Crohn's Disease
• Type 1 Diabetes
• Esophageal Squamous Cell Carcinoma (ESCC)
• Stomach Cancer (Gastric Cardia Adenocarcinoma)

What really surprised me is that I have only an average risk of having Coronary Heart Disease.

(2)  Carrier Status
         The variant is present for:

• Hemochromatosis (iron overload)

In people with hemochromatosis, iron builds up in the body, causing organ damage— especially in the liver. (23andme.com)

  (3)  Drug Response
         Increased chance of hypersensitivity to:

•  Oral Contraceptives, Hormone Replacement Therapy and Risk of Venous Thromboembolism



Warfarin is a drug that can help prevent blood clots. (23andme.com)

• Warfarin (Coumadin®) Sensitivity
• Heroin Addiction (Really?!  I do not think I need to worry about this one!) 
• Postoperative Nausea and Vomiting (This is interesting... as I have never experienced this before.)

(4)  Traits

•  Lactose Intolerance:  Likely tolerant
• Malaria Resistance:  Not resistant  (There goes my African safari!)
• Norovirus Resistance:  Not resistant

The good news is that I did not have an increased risk of Alzheimer's, Parkinson's Disease, MS, Lou Gehrig's Disease, or most cancers.  I have to admit this does relieve my mind. 

I do know that none of this is carved in stone.  However, it does give me a good idea of what to be vigilant about.  

Tonight, I sent out invitations to five of those in Relative Finder who showed the highest percentages of matching my DNA profile.  I did not have anyone closer than a 4th cousin show up, but the way I'm collecting cousins lately (A story for another blog post!), what's a few more?